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Thrombosis Risk Panel

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Venous thromboembolism

Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism, is a major cause of preventable morbidity and mortality. Individuals with inherited thrombophilia have a genetic predisposition to abnormal blood clotting, placing them at significantly increased risk of VTE.

Thromboprophylaxis, including anticoagulation therapy and mechanical prevention measures, is routinely used in individuals with an elevated VTE risk.

Thromboprophylaxis in pregnancy

During pregnancy, normal physiological changes increase the body’s tendency to form blood clots. For individuals with inherited thrombophilia, this risk becomes even higher during both pregnancy and the postpartum period due to additional pro-thrombotic changes.

Screening for genetic predisposition supports preventive strategies, informed reproductive planning, and tailored clinical management.

Designed for prevention

For women who have recently been pregnant assessing the risk of blood clotting can help guide and support safety and wellbeing.

Using fluorescent ARMS allele-specific amplification, the Yourgene® Thrombosis Risk Panel detects the four most relevant genetic mutations linked to increased blood clotting risk, including point mutations, insertions, and deletions in DNA.

  • Factor V (R506Q)
  • Factor II (20210 G>A)
  • MTHFR (677 C>T & 1298 A>C)

Rapid Workflow. Faster Patient Results

in vitro diagnostic
In vitro diagnostic
Single tube assay
Single tube assay
Timer
~30 min hands on time
Optimally balanced primers
Optimally balanced primers

Clinical Confidence

One PCR

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One analysis

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One report

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Recurrent Pregnancy Loss Complete investigation

Recurrent pregnancy loss affects 15-20% of women with MTHFR variants. 

Inherited thrombophilia elevates VTE risk but are also associated with pregnancy complications, including miscarriage and recurrent pregnancy loss.

Learn more about the Yourgene® Pregnancy Loss assay
Yourgene Health

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