Prenatal Diagnostic Testing
Autosomal trisomies are among the most common chromosomal abnormalities detected during pregnancy and can significantly disrupt expected fetal development. Some trisomies are compatible with live birth but they are associated with serious developmental and medical complications, while many other chromosomal abnormalities are incompatible with life.
Accurate and timely diagnosis during pregnancy is therefore critical to support clinical counselling and informed pregnancy management.
Fetal DNA for analysis is obtained through sample collection via amniocentesis or Chorionic Villus Sampling (CVS), enabling confirmatory testing following high-risk screening results during prenatal/antenatal testing.
Designed for Detection. Trusted for Diagnosis.
The Yourgene® QST*R range delivers rapid, reliable confirmatory detection of common aneuploidies using a panel of highly informative chromosomal markers.
Designed for diagnostic confidence, the single-tube assay utilises Quantitative Fluorescent Polymerase Chain Reaction (QF-PCR) technology, where fluorescent dye-labelled primers amplify highly polymorphic short tandem repeat (STR) regions on the chromosomes of interest.
The Yourgene QST*R Range assay detects:
- Trisomy 13 (Patau syndrome)
- Trisomy 18 (Edwards syndrome)
- Trisomy 21 (Down syndrome)
- X and Y chromosomal abnormalities
Rapid Prenatal Aneuploidy Analysis.
The Yourgene® QST*R Base assay is a multiplex assay containing 22 markers across chromosomes 13, 18, 21, X and Y, enabling rapid confirmatory detection of common autosomal trisomies and sex chromosome aneuploidies.
The Base assay can be combined with our optional reflex kits, providing additional chromosomal markers for follow-up testing. This flexible approach supports comprehensive diagnostic coverage and delivers reliable results.
The Yourgene® QST*R Base assay has received IVDR certification!
A product with IVDR certification enables clinician and patient confidence in a higher quality test – where accuracy matters
View our IVDR certification here.
Yourgene® QST*R Range
- Yourgene® QST*R Base (IVDR)
- Yourgene® QST*R Plus Trisomy 13
- Yourgene® QST*R Plus Trisomy 18
- Yourgene® QST*R Plus Trisomy 21
- Yourgene® QST*R Plus Trisomy XY
Rapid Workflow. Faster Patient Results.
*The Yourgene® QST*R Base assay is CE marked in accordance with the IVDR.
The other assays in the Yourgene® QST*R Range are CE marked in accordance with IVDD. Kits are also available as Research Use Only (RUO) products.
Trust your results. Supporting Clinical Confidence
- Simple set up – one tube per sample
- Rapid – minimum hands on time, just add DNA
- One step protocol – DNA extraction to PCR
- Reduced risk of sample mix-up
- Efficient – fewer consumables, reduced cost
- Validated for use on the ABI3500 and SeqStudio Genetic Analyzers
- Highly informative – multiplexed 5 dye chemistry
- No post-PCR manipulation
- One capillary per sample
- Cost effective – less instrument consumables
- GeneMarker™ and GeneMapper® software applications
- Simple data review and analysis
- Easy to use intuitive software
- Informative single page report
- No data transfer required
